K. Zhubanov Regional State University is a successor of Aktobe Teacher Training Institute founded by the Resolution of the Central Committee of the Communist Party of Kazakhstan and Council of Ministers of the Kazakh SSR No. 261 of April 15, 1966.
Originally 250 students of full-time department received education at two faculties – Physics and Mathematics and Philology, 100 students of Correspondence Department studied under specialties of Physics and Mathematics, Russian language and literature, Russian language and literature at the Kazakh school. Classes were conducted by 23 lecturers, including 4 Candidates of Science and an Associate Professor. Candidates of Science M.O. Tolegenov, P.Ya. Shibayev, V.N. Smirnova, a young postgraduate specialist A.M. Moldakhanov were among the first lecturers by the assignment of the Ministry of Higher and Secondary Vocational Education.
By the resolution of the Council of Ministers of the Kazakh SSR No. 72 of February 23, 1990 Aktobe Teacher Training Institute was assigned the name of the first professor-linguist Kudaybergen Kuanovich Zhubanov.
The institute was reorganized into K. Zhubanov Aktobe University by the resolution of the Government of the Republic of Kazakhstan No. 573 of May 7, 1996. K. Zhubanov Aktobe University was given the status of the state university by the resolution of the Government of the Republic of Kazakhstan No. 163 of January 31, 2001.
Due to the fact that Aktobe Teacher Training Institute was removed from the structure of the university K. Zhubanov Aktobe State University was created again by the resolution of the Government of the Republic of Kazakhstan No. 128 of February 3, 2004.
K. Zhubanov Aktobe Regional State University and Aktobe State Teacher Training Institute were reorganized by the resolution of the Government of the Republic of Kazakhstan No. 529 of May 29, 2015 by merge into K. Zhubanov Aktobe Regional State University.